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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRP1
All Species:
20
Human Site:
S225
Identified Species:
48.89
UniProt:
O95267
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95267
NP_001122074.1
797
90402
S225
F
K
S
F
R
R
I
S
F
S
D
Y
Q
N
Y
Chimpanzee
Pan troglodytes
XP_001165459
689
78238
L160
P
I
E
L
A
E
H
L
T
F
L
E
H
K
S
Rhesus Macaque
Macaca mulatta
XP_001092164
797
90549
S225
F
K
S
F
R
R
I
S
F
S
D
Y
Q
N
Y
Dog
Lupus familis
XP_535429
624
71069
L95
Q
W
V
Q
L
M
V
L
S
R
P
T
P
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1S3
795
90285
S225
F
K
S
F
R
R
I
S
F
S
D
Y
Q
N
Y
Rat
Rattus norvegicus
Q9R1K8
795
90226
S225
F
K
S
F
R
R
I
S
F
S
D
Y
Q
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511025
724
82163
E195
Y
V
I
H
G
C
L
E
D
N
P
T
L
E
R
Chicken
Gallus gallus
XP_001233089
744
85631
S215
W
V
Q
L
M
V
L
S
R
P
T
P
Q
L
R
Frog
Xenopus laevis
Q6NTL4
791
90153
S221
F
K
A
F
R
R
I
S
F
S
D
Y
Q
N
Y
Zebra Danio
Brachydanio rerio
NP_001103934
708
80321
Y179
S
F
T
D
Y
Q
S
Y
V
I
H
G
C
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.9
98.3
74.9
N.A.
90.3
89.8
N.A.
48.6
70.7
71
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.8
99
76.6
N.A.
93.2
93.2
N.A.
64.1
81
81.8
62.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
100
100
N.A.
0
13.3
93.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
6.6
N.A.
100
100
N.A.
20
26.6
100
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
50
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
0
10
0
0
0
10
0
10
0
% E
% Phe:
50
10
0
50
0
0
0
0
50
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
10
0
0
10
0
0
0
10
0
10
0
0
% H
% Ile:
0
10
10
0
0
0
50
0
0
10
0
0
0
0
0
% I
% Lys:
0
50
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
20
10
0
20
20
0
0
10
0
10
20
10
% L
% Met:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
50
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
20
10
10
0
0
% P
% Gln:
10
0
10
10
0
10
0
0
0
0
0
0
60
10
0
% Q
% Arg:
0
0
0
0
50
50
0
0
10
10
0
0
0
0
20
% R
% Ser:
10
0
40
0
0
0
10
60
10
50
0
0
0
0
10
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
10
20
0
0
0
% T
% Val:
0
20
10
0
0
10
10
0
10
0
0
0
0
0
10
% V
% Trp:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
10
0
0
0
50
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _